Ogdie A. et al., Experiences and Treatment Preferences in Patients With Psoriatic Arthritis: A Cross-Sectional Study in the ArthritisPower Registry. Rheumatology and Therapy. 2022 Apr;9(2):735-751
The study aimed to improve our understanding of the burden of psoriatic arthritis (PsA) symptoms, from joint pain to nail pitting, and the impact of the disease on patients’ physical, social, and emotional functioning. The study also evaluated patients’ treatment preferences, including the mode and frequency of treatment administration.
Why it’s Important
Psoriatic arthritis is a chronic inflammatory disease that develops in up to 30% of patients with psoriasis. Psoriatic arthritis symptoms include joint pain, joint swelling, fatigue, and pruritis, among many others. Additionally, a large percentage of individuals with PsA also present with anxiety and depression, further contributing to a reduction in patient quality of life (QoL).
Despite recent advances in the treatment of PsA, however, less than 50% of patients in clinical trials reach pre-defined treatment targets.
This could be due to the heterogeneity of the disease and/or the impact of mental and emotional aspects of PsA on patient outcomes. Engaging patients to identify such unmet treatment-related needs may ultimately lead to better care.
Patients (N=332) were recruited from ArthritisPower, a rheumatology research registry, and were asked to complete a survey comprised of a series of questions surrounding their experiences of living with PsA.
A best-to-worst scaling method was used to rank the burden of 11 PsA symptoms, including skin pain and itching, and the importance of improvement on 9 PsA-related disease impacts, including sleep quality and the ability to do daily activities.